Janus Henderson Investors

Activity from announced rounds

All recorded activity

Janus Henderson Investors is an asset manager with specialist healthcare investing capabilities, including a biotechnology strategy that invests in both public and private companies.

Its Biotechnology Innovation strategy uses long-term, research-intensive analysis across the biotech landscape. The healthcare team evaluates businesses addressing unmet medical needs and technologies intended to improve the efficiency and cost of care.

The biotechnology strategy combines long investments with short selling in its portfolio construction. Private-company investment is part of this specialist asset-management activity, alongside the firm’s broader range of investment strategies.

Sources
Rounds participated in
18
Confirmed lead rounds
1
12 roles undisclosed
New companies
18
First participation on record · 0 follow-on
Funding in participating rounds
$3.3B
18 disclosed · full round size, not this investor’s share

By stage

Series C+8
Series A4
Series B4
Undisclosed2

By primary sector

Biotech15
Climate tech1
Healthtech1
Space tech1

By country

United States15
United Kingdom2
1

Rounds

18 in all activity
Star Therapeutics

Biotechnology company discovering and developing antibody therapies for diseases with significant unmet need.

$200MPrivate financing
Lead
OMass Therapeutics

OMass Therapeutics develops small-molecule medicines for endocrine and immune diseases using a platform that measures drug targets in their biological surroundings.

$310MSeries C
Participant
Soufflé Therapeutics

Soufflé Therapeutics develops targeted RNA medicines for patients with muscle disorders and heart failure.

$135MSeries B
Participant
Encoded Therapeutics Inc.

Encoded develops precision gene therapies for neurological disorders, led by ETX101, a gene-regulation therapy for people with SCN1A-positive Dravet syndrome.

$275MSeries F
Participant
FORM ENERGY

Long-duration iron-air batteries designed to store electricity for multi-day grid needs.

$750MSeries G
Participant
Triveni Bio

Develops novel antibody treatments for immunological and inflammatory disorders

$65MSeries C
Role not disclosed
Calyxo

Develops medical devices for kidney stone treatment and removal

$40MSeries F
Role not disclosed
Ambrosia Biosciences

Drug-discovery company developing oral small-molecule treatments for obesity and metabolic disorders.

$100MSeries B
Participant
Poplar Therapeutics

Developing a new class of anti-IgE therapy to treat food allergy and other atopic conditions

$45MSeries A+
Role not disclosed
CesiumAstro

CesiumAstro develops communications technology for space and defense applications.

$470MSeries C
Role not disclosed
TRex Bio

Develops precision immunoregulatory medicines based on tissue Treg biology

$50MUndisclosed
Role not disclosed
Think Bioscience

Develops small molecule drugs for historically challenging drug targets

$55MSeries A
Role not disclosed
Parabilis Medicines

Develops medicines targeting historically undruggable protein targets in cancer

$305MSeries F
Role not disclosed