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United States · Biotech
Encoded develops precision gene therapies for neurological disorders, led by ETX101, a gene-regulation therapy for people with SCN1A-positive Dravet syndrome.
Encoded engineers gene therapies to target specific cell types and regulate disease-relevant genes. Its lead candidate, ETX101, is designed to increase SCN1A expression in inhibitory neurons, addressing the underlying gene insufficiency associated with SCN1A-positive Dravet syndrome rather than only managing seizures symptom by symptom.
ETX101 is being studied as a potential one-time treatment for infants, children and adolescents with Dravet syndrome. The company reported that the candidate had entered pivotal development in 2026, following Phase 1/2 trials; its broader pipeline applies the vector-engineering platform to additional neurological disorders. These are investigational therapies, not marketed treatments.
| Announced | Round | Amount | Investors |
|---|---|---|---|
| Series F | $275M | GV — LeadARCH Venture Partners — ParticipantBraidwell LP — ParticipantFarallon Capital Management — ParticipantIllumina Ventures — ParticipantInvus — ParticipantJanus Henderson Investors — ParticipantMatrix Capital Management — ParticipantNolan Capital — ParticipantRTW Investments — ParticipantSoftBank Vision Fund 2 — ParticipantVenrock — Participant |