ARCH Venture Partners

Activity from announced rounds

All recorded activity

ARCH Venture Partners creates and backs companies built on scientific discoveries, with a healthcare focus on technologies that prevent, detect and treat disease.

The firm works through company formation as well as financing, using a network of partners to translate science into an operating business. It sizes capital to the development requirements, with investments ranging from very early commitments to hundreds of millions of dollars per company.

Its long-term model accommodates scientific programmes that need substantial development before commercial scale. Founders and researchers can engage around the creation of a company, rather than waiting until a conventional growth-stage investment case is established.

Sources
Rounds participated in
15
Confirmed lead rounds
0
12 roles undisclosed
New companies
15
First participation on record · 0 follow-on
Funding in participating rounds
$2.4B
15 disclosed · full round size, not this investor’s share

By stage

Series B7
Series A3
Undisclosed3
Series C+2

By primary sector

Biotech14
Hardware1

By country

United States13
Sweden1
United Kingdom1

Rounds

15 in all activity
Soufflé Therapeutics

Soufflé Therapeutics develops targeted RNA medicines for patients with muscle disorders and heart failure.

$135MSeries B
Participant
Encoded Therapeutics Inc.

Encoded develops precision gene therapies for neurological disorders, led by ETX101, a gene-regulation therapy for people with SCN1A-positive Dravet syndrome.

$275MSeries F
Participant
Moonwalk Biosciences

Moonwalk Biosciences is developing adipose-targeted siRNA medicines for obesity and cardiometabolic disease. Its lead programs are designed to alter fat-tissue pathways while limiting effects on other tissues, with the lead obesity candidate in IND-enabling development ahead of planned human testing in 2027.

$70MSeries B
Participant
LifeMine Therapeutics

Develops fungal genome-derived therapeutics for organ transplant rejection

$263MSeries D+Series E
Role not disclosed
Oratomic

Builds quantum computers using lasers to hold individual atoms in place

$300MSeries A
Role not disclosed
Ollin Biosciences

Develops bispecific antibody therapies for retinal vascular diseases including diabetic macular edema and wet AMD

$330MSeries B
Role not disclosed
SonoThera

Develops ultrasound-mediated nonviral genetic medicines

$125MSeries B
Role not disclosed
City Therapeutics

City Therapeutics develops RNA-interference therapeutics and an engineering platform across disease areas.

$99.5MSeries B
Role not disclosed
Countable Labs

Develops single-molecule PCR technology for genomics measurement

$26MSeries A
Role not disclosed
CREATE Medicines

Develops in vivo immune programming platform for scalable, repeat-dose immunotherapies

$122MSeries B
Role not disclosed
Moleculent

Decodes cellular networks to advance human health

$20MUndisclosed
Role not disclosed
Lightcast

Develops functional single-cell analysis tools and platforms for life science research

$27MUndisclosed
Role not disclosed
Mirador Therapeutics

Develops next-generation therapies for immune-mediated inflammatory and fibrotic diseases

$250MSeries B
Role not disclosed
Vizgen

Builds technologies for spatial biology and multi-omics innovation

$48MSeries A
Role not disclosed
Parabilis Medicines

Develops medicines targeting historically undruggable protein targets in cancer

$305MSeries F
Role not disclosed