General Catalyst

Semi-autonomous humanoid robots for hazardous industrial and public-safety work.

Melius gives creative teams a shared workspace where AI agents produce images, video and audio, taking on repetitive production work so people can focus on concepts and creative direction.

Varda builds spacecraft that manufacture materials in low Earth orbit and return them to Earth. Its capsules support microgravity pharmaceutical development and materials processing, followed by controlled reentry and post-flight analysis of returned payloads.

Builds a foundation model training AI agents on spatial reasoning from video game data

A proactive AI assistant for email-heavy professionals that detects commitments in Gmail, prepares the research, documents, replies or meetings needed to fulfil them, and waits for user approval before acting.

Complir helps retailers and brands manage product safety and regulatory compliance across the markets where they sell.

A health-benefits platform that lets employers set healthcare budgets while employees choose insurance and eligible care to fit their needs.

Integral combines AI-assisted accounting, tax and payroll operations with licensed professionals for small and mid-sized businesses in Germany. Its platform connects bank transactions, receipts, invoices and payroll data, automates recurring work and keeps experts responsible for review and advice.

Develops Devin, an autonomous AI software engineer serving enterprises including Mercedes-Benz and NASA

AI-powered network connecting doctors, pharmacies, payers, and biopharma to streamline patient access to treatments

Poke is a consumer AI assistant designed to operate through messaging platforms.

Structured data and AI agents for clinical development and pharmaceutical trial operations.

Graylark builds Raven, an AI intelligence tool that helps verified agencies and investigative teams analyze their own imagery.

Physical AI platform capturing real-world lab science into machine-readable data

Arga Labs creates sandbox environments with service twins so companies can safely test and train AI agents before deployment.

Blank Street runs compact neighborhood cafes serving specialty coffee, matcha and fresh, locally sourced food.

Primero connects the business systems and data used by large companies, then deploys AI workflows with human oversight.

Builds low-cost, mass-producible hypersonic strike missiles for defense

Builds infrastructure for training and serving personally trainable AI agents

Develops AI-powered autonomous directed-energy systems to detect and neutralize drone threats

AI-native platform automating inventory, pricing and other critical decisions for spare parts businesses

Intelligent email inbox that prepares work proactively

Simulates how procedural devices perform across virtual patients before clinical deployment

Neko Health provides body-scanning technology combined with bloodwork to assess health

Software-driven manufacturing company modernizing wire harness production

Building AI models to accelerate pre-clinical drug discovery

Develops AI software and autonomous systems for military and national security applications

Builds quantum computers using lasers to hold individual atoms in place

Makes it cheaper and easier to run open source AI models at scale

Automates chronic care for older adults using AI