General Catalyst

Semi-autonomous humanoid robots for hazardous industrial and public-safety work.

Melius gives creative teams a shared workspace where AI agents produce images, video and audio, taking on repetitive production work so people can focus on concepts and creative direction.

Varda builds spacecraft that manufacture materials in low Earth orbit and return them to Earth. Its capsules support microgravity pharmaceutical development and materials processing, followed by controlled reentry and post-flight analysis of returned payloads.

Builds a foundation model training AI agents on spatial reasoning from video game data

A proactive AI assistant for email-heavy professionals that detects commitments in Gmail, prepares the research, documents, replies or meetings needed to fulfil them, and waits for user approval before acting.

A health-benefits platform that lets employers set healthcare budgets while employees choose insurance and eligible care to fit their needs.

Develops Devin, an autonomous AI software engineer serving enterprises including Mercedes-Benz and NASA

AI-powered network connecting doctors, pharmacies, payers, and biopharma to streamline patient access to treatments

Structured data and AI agents for clinical development and pharmaceutical trial operations.

Physical AI platform capturing real-world lab science into machine-readable data

Arga Labs creates sandbox environments with service twins so companies can safely test and train AI agents before deployment.

Builds low-cost, mass-producible hypersonic strike missiles for defense

Builds infrastructure for training and serving personally trainable AI agents

Develops AI-powered autonomous directed-energy systems to detect and neutralize drone threats

Simulates how procedural devices perform across virtual patients before clinical deployment