Y Combinator (YC)

Open-source AI models and the Hermes agent, which retains project memory and reusable skills across tasks.

Santé gives wine and spirits retailers one system for in-store sales, e-commerce, delivery orders, marketing and subscriptions.

Flai gives automotive dealerships AI tools to answer customer calls, capture leads and schedule sales and service appointments.

A platform for designing and manufacturing naturally modified mRNA medicines.

Vitalize helps hospital teams coordinate staffing and capacity as patient demand shifts.

Training environments and benchmarks that measure how AI agents perform financial services work.

Autonomous hypersonic cargo rockets are being developed to deliver military micro-payloads to remote or contested locations.

AI agents that run growth marketing, advertising and search optimization for software companies.

flowscope automates enterprise work by connecting business processes and using AI to reduce repetitive operational tasks.

AI models designed to discover oral medicines for diseases currently treated with injectable drugs.

Hubble Network connects ordinary Bluetooth devices to satellites, extending asset tracking beyond the reach of cellular networks.

AI-powered software that automates sales tax and VAT compliance for global businesses.

Confido connects accounting, finance, sales and operations data so consumer brands can manage deductions, trade spending and supply plans together.

Fast GitHub Actions runners paired with AI agents that optimize continuous integration workflows.

CatchBack turns physical trading cards into a digital mystery-pack marketplace. Customers can open packs, see transparent odds and use trading and instant buyback features that make collectible pricing and resale more accessible.

Independent benchmarks that test how well AI models control real robots.

AI agents that automate software testing and help teams improve application quality.

An AI fundraising workspace that helps founders identify investors, research firms and manage venture rounds.

Kalinda uses AI to help plaintiff-side class action and mass tort firms review case information and qualify potential claims.

An AI actuarial platform that helps companies model and manage risks retained through their own insurance captives.

Open-source healthcare data infrastructure unifying patient records for clinicians

AI platform automating medical coding and revenue assurance for health systems

Builds AI agent harnesses for asset managers' proprietary research and data

Foundation models for understanding, designing and controlling hardware and physical systems.

AI software that extracts and verifies financial documents to help lenders assess borrowers.

MIT spinoff building factory-built compact pressurized water reactors

Thunder Compute virtualizes GPUs so multiple workloads can share capacity and data centers can use existing hardware more efficiently.

AI agents that map, document and modernize legacy COBOL applications.

A machine-native browser engine that turns websites into structured workflows AI agents can execute.

Gamgee develops personalized mRNA vaccines for dogs with cancer, designed from the genetic profile of each dog’s tumor.