A different target for migraine prevention
Slate’s lead program, SLTE-1009, targets PACAP, a pathway distinct from the CGRP target used by existing migraine medicines. Licensed from DartsBio Pharmaceuticals, the antibody was engineered for a longer half-life and subcutaneous administration.
Preparing for clinical development
RA Capital Management, Forbion and Foresite Capital co-led the $130 million Series A, joined by another undisclosed biotech investor. At launch, Slate planned to begin Phase 1 testing in mid-2026 and was also advancing an undisclosed pipeline of headache treatments.