General Catalyst

Physical AI platform capturing real-world lab science into machine-readable data

Builds a foundation model training AI agents on spatial reasoning from video game data

Builds low-cost, mass-producible hypersonic strike missiles for defense

Builds infrastructure for training and serving personally trainable AI agents

Develops AI-powered autonomous directed-energy systems to detect and neutralize drone threats

AI-native platform automating inventory, pricing and other critical decisions for spare parts businesses

Intelligent email inbox that prepares work proactively

Simulates how procedural devices perform across virtual patients before clinical deployment

Neko Health provides body-scanning technology combined with bloodwork to assess health

Software-driven manufacturing company modernizing wire harness production

Building AI models to accelerate pre-clinical drug discovery

Develops AI software and autonomous systems for military and national security applications

Builds quantum computers using lasers to hold individual atoms in place

Makes it cheaper and easier to run open source AI models at scale

Automates chronic care for older adults using AI

Manufactures AI-native industrial robots for automation

Provides consumer fintech platform helping everyday Americans improve their financial lives

Brings frontier technology to the real economy with AI-native business operating system

Builds AI-native engineering simulation software compressing months of design work into seconds for manufacturing and defence

Provides financial infrastructure for corporate cards, invoicing, and expense management

AI-powered workforce operations platform helping businesses manage HR, finance, and IT through agentic workflows

Develops AI-designed CAR T therapies for solid tumors using spatial biology

Provides security and governance for AI agents

Develops Devin, an autonomous AI software engineer serving enterprises including Mercedes-Benz and NASA

Preventive health platform analysing 110+ blood biomarkers with AI-driven personalised health insights

Combines travel booking with co-branded credit cards and mobile payments

Builds a gamified social simulation platform where users roleplay characters inside AI-generated social worlds

Trains workforces in AI and tech skills through apprenticeships for enterprise employers

AI-powered network connecting doctors, pharmacies, payers, and biopharma to streamline patient access to treatments

Provides AI-native platform for securities compliance in financial institutions