Autopoiesis Sciences

From a research question to evidence and experiments

Autopoiesis Sciences operates Aristotle, a research assistant that helps scientists explore literature, form testable hypotheses and challenge experimental designs. A researcher supplies a question and supporting files, then can inspect cited sources and reasoning or check claims for uncertainty and conflicting evidence. Its different modes support literature synthesis, hypothesis generation and skeptical review. The company says thousands of researchers use Aristotle, including people at pharmaceutical companies, universities and regulators; these affiliations describe individual use rather than institutional purchasing contracts.

The company also develops Columbus-1 for investigations that run across many steps. Its published architecture combines a persistent record of hypotheses, evidence and rejected approaches with a controller that switches the model between exploration, execution and self-critique. Autopoiesis reports demonstrations in security research and rocket design, including simulations and manufacturing files. These are company-reported research results; its broader goal of autonomous scientific discovery remains an ongoing development program alongside the available Aristotle service.